Erosive arthritis in relapsing polychondritis.

نویسندگان

  • A S Jawad
  • M Burrel
  • K L Lim
  • D G Scott
چکیده

We report the case history of a 57 year old man who has suffered from typical deforming, relapsing polychondritis for 13 years. He has also developed erosive destructive seronegative polyarthritis involving some of his distal interphalangeal, proximal interphalangeal, metacarpophalangeal, intercarpal, wrist, intertarsal and metatarsophalangeal joints. The distribution of joint involvement in the small joints of the hands and feet is asymmetrical. Both hips and knee joints have also been involved necessitating bilateral total hip and right total knee replacement. The articular associations with relapsing polychondritis are discussed.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Cartilage-specific autoimmunity in animal models and clinical aspects in patients – focus on relapsing polychondritis

Relapsing polychondritis is an autoimmune disease in which an inappropriate immune response destroys cartilage. Cartilage of the ears, larynx and nose rather than spine and joint cartilage is affected by a chronic relapsing and erosive inflammation. Several animal models for relapsing polychondritis have been published in which immunization with various cartilage proteins induces a variety of c...

متن کامل

Auricular chondritis associated with systemic joint and cartilage inflammation in a cat.

An adult, Japanese domestic cat presented with bilateral swelling, distortion, and erythema of ears and deformation of the limbs. Biopsy of the pinnae confirmed auricular chondritis. These lesions and the cat's general condition subsequently deteriorated, and the cat died. At necropsy, chondral changes were present in the pinnae, costae, larynx, trachea, and limbs. Histopathologically, these ch...

متن کامل

Tracheal stenosis due to relapsing polychondritis in rheumatoid arthritis.

Upper airways disease is seen in 50-80% of necropsies in patients dying with rheumatoid arthritis.' Most commonly the larynx is affected by synovitis of the cricoarytenoid joints, producing structural and functional changes with hoarseness, dyspnoea and sore throat. Submucosal granulomas in the postcricoid and subhyoid regions are associated with oedema and fibrosis producing substantial suprag...

متن کامل

Relapsing polychondritis mimicking rheumatoid arthritis.

A woman with relapsing polychondritis presented with progressive and deforming polyarthritis (but always negative for rheumatoid factor) 14 years before the appearance of typical clinical and histological changes of nasal and auricular cartilage destruction.

متن کامل

Hypertrophic Pachymeningitis as an Early Manifestation of Relapsing Polychondritis: Case Report and Review of the Literature

Neurological involvement in relapsing polychondritis (RP) is relatively rare. We describe the case of an 80-year-old man who presented with hypertrophic pachymeningitis (HP) together with arthritis as the first manifestation of RP. Auricular chondritis, which subsequently determined the diagnosis of RP, occurred a few weeks after the detection of HP. The neurological symptoms, as well as arthri...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Postgraduate medical journal

دوره 66 779  شماره 

صفحات  -

تاریخ انتشار 1990